As shown in Figure 1B, the HPSE expression was significantly increased in bladder urothelial carcinoma (BLCA), breast invasive carcinoma (BRCA), cholangiocarcinoma (CHOL), esophageal carcinoma (ESCA), lung adenocarcinoma (LUAD), lung squamous carcinoma (LUSC), stomach adenocarcinoma (STAD), and thyroid carcinoma (THCA). The gene discussed is HPSE; the disease is invasive breast carcinoma.