The major finding of the present study revealed that miR-181b was downregulated in SCAP compared with healthy controls, and showed significant association with the white blood cell count, absolute neutrophils, C-reactive protein concentration, and PSI scores of SCAP patients, which are important clinical and laboratory characteristics of patients (Mukamal et al., 2010; Rhim et al., 2011). Here, CRP is linked to syringocystadenoma papilliferum.