SPTLC1 and amyotrophic lateral sclerosis: After identifying variants in serine palmitoyltransferase, long-chain base subunit 1 (SPTLC1; OMIM, 605712) in all 3 cases, we also screened patients with juvenile ALS from Turkey for SPTLC1 variants and identified a fourth patient carrying an SPTLC1 variant.