Tumor cells expressed relatively high levels of EGFR, FGFR1, and FGFR2, while their corresponding ligands, such as COPA, GRN, HBEGF, FGF2, FGF7, and FGF18, were widely expressed in fibroblast cells (Figure 7C, E). This evidence concerns the gene FGFR1 and neoplasm.