Activated CAFs could significantly induce the invasion of ESCC cells, whereas the invasion of KYSE30 and KYSE410 cells was largely inhibited when IL‐6, IL‐7, IL‐8, CCL5, or TGF‐β1 Ab (10 μg/ml) was added to the coculture transwell system (Figure 8C). The gene discussed is CXCL8; the disease is esophageal squamous cell carcinoma.