Overall, the current study proved that transfer of NEAT1 via PCa‐derived exosomes altered the RUNX2 expression, by means of competitively binding to miR‐205‐5p and regulating the SFPQ/PTBP2 axis, consequently, leading to the osteogenic differentiation of hBMSCs (Figure 8). This evidence concerns the gene RUNX2 and posterior cortical atrophy.