TFG and nervous system disorder: TFG is an essential protein in the regulation of vesicular trafficking between endoplasmic reticulum and Golgi, and several TFG mutations have been associated with different neurological disorders, including hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN‐P), Charcot‐–Marie–Tooth disease, and recessive hereditary spastic paraparesis (Yagi et al, 2016).