CRYBA1 and age-related macular degeneration: Further corroborating the idea that impaired lysosomal function is pathognomonic to ARMD, animal models deficient in CRYBA1/bA3/A1‐crystallin display impaired lysosomal acidification in RPE, culminating in RPE degeneration and signs of ARMD (Valapala et al, 2014).