Very strikingly, in pancreatic cancer, TGFβ‐mediated EMT depends almost exclusively on ZEB1, since Zeb1 knockout in KPC cells blocks more than 90% of TGFβ‐induced alterations in gene expression, despite of Snai1 upregulation during TGFβ treatment (Krebs et al, 2017). The gene discussed is TGFB1; the disease is familial pancreatic carcinoma.