Several studies could show that knockdown of the EMT‐TF ZEB1 is sufficient to elicit MET in vitro in carcinoma cell lines of different entities (Eger et al, 2005; Spaderna et al, 2006; Spaderna et al, 2008) and that depletion of Zeb1 in a genetic mouse model of pancreatic cancer fixes the tumor cells in an epithelial MET state (Krebs et al, 2017). This evidence concerns the gene ZEB1 and neoplasm.