Observations in patients support a clinical relevance of EMT‐associated pro‐survival stress adaptation, exemplified by analysis of post‐therapy specimens, e.g., in esophageal and breast cancer after chemotherapy and in CRC after radiotherapy, showing decreased E‐cadherin and elevated SNAIL and Vimentin levels (Creighton et al, 2009; Kawamoto et al, 2012; Hara et al, 2014). The gene discussed is SNAI1; the disease is breast cancer.