BMI: Body mass index, FBS: Fasting blood sugar, FI: Fasting insulin, FSH: Follicle-stimulating hormone, TSH: Thyroid-stimulating hormone, LH: Luteinizing hormone, SHBG: Sex hormone-binding globulin, DHEAS: Dehydroepiandrosterone sulfate, PRL: Prolactin, TG: Triglyceride, HOMA-IR: Homeostasis model assessment of insulin resistance, QUICKI: Quantitative insulin-sensitivity check index. All data are presented as Mean ± SD. *P-value < 0.05 is considered significantly different using independent sample t test. ♦IQR: interquartile range. The gene discussed is SHBG; the disease is Insulin resistance.