As the lungs are the organ most affected by COVID-19, studies have been carried out that evaluate the response of pluripotent stem cells induced to an epithelial alveolar phenotype when infected with SARS-CoV-2, finding that they present a global transcriptomic change characterized by the expression of encoded cytokines by NF-κB genes and epithelial interferon late responses [47]. This evidence concerns the gene NFKB1 and COVID-19.