Compared with the WT mice, TAC surgery led to severer cardiac hypertrophy in the Fabp3-null mice, revealed as higher thickness of the interventricular septum (IVS; d: 1.56 ± 0.03 vs. 1.17 ± 0.04; IVS; s: 2.02 ± 0.05 vs. 1.63 ± 0.03; F3-KO vs. WT) and left ventricular posterior wall thickness (LVPW; d: 1.38 ± 0.08 vs. 1.11 ± 0.06; LVPW; s: 1.82 ± 0.07 vs. 1.60 ± 0.07; F3-KO vs. WT) in the F3-KO mice; meanwhile, these parameters were comparable in sham groups (Figures 2B,C). Here, FABP3 is linked to cardiac hypertrophy.