APOB and coronary artery disorder: As the common pathological basis of CAD (4) and IS (5), atherosclerosis is the result of chronic inflammation (6) and abnormal lipid metabolism, such as increased levels of triglyceride (TG) (7), apolipoprotein (Apo) B (8), low-density lipoprotein cholesterol (LDL-C) (9), and total cholesterol (TC) (10), along with reduced levels of ApoA1 (8) and high-density lipoprotein cholesterol (HDL-C) (11) in serum.