In the multivariate COX proportional hazard model, 11 variables were identified as independent predictors for SVG occlusion: sex, diabetes mellitus, smoking, dyslipidemia, hyperuricemia, prior percutaneous coronary intervention (PCI), on-pump surgery, SVG number, lesion vessel number (including only vessels of the left anterior descending branch, circumflex artery, and right coronary artery), use of angiotensin-converting enzyme inhibitors (ACEI)/angiotensin receptor blockers (ARB), and use of calcium channel blockers (CCB; Table 2). This evidence concerns the gene ACE and metabolic syndrome.