Generally, the response rate was higher in patients with CPS ≥ 10 vs. CPS < 10 in PD-L1 expression level (83.3 vs. 50%); higher in TMB ≥ 10 vs. < 10 (75 vs. 33%); and higher in patients with LN only disease vs. non-LN disease (100 vs. 57.1%). Here, CD274 is linked to lobular neoplasia.