The global percentage of cancers in which regulators have an effect on a pathway showed that ACE1 was involved in the activation of apoptosis, DNA damage, epithelial–mesenchymal transition (EMT), hormone ER, hormone AR, RAS/MAPK, and RTK pathways and the inactivation of the cell cycle and TSC/mTOR pathways. The gene discussed is MTOR; the disease is cancer.