TRPM7 and glioblastoma: TRPM7 expression in glioblastoma cells was found to be positively correlated with Notch1 signaling activity and CD133 and ALDH1 expression; briefly, downregulation of TRPM7 by siTRPM7 decreased Notch1 signaling whereas upregulation of TRPM7 increased Notch1 signaling (Wan et al., 2020).