PF4 and chronic kidney disease: As shown in Table 1, the first set (HTN/N) of differentially expressed proteins consisted of those who had BP abnormalities, regardless of whether their underlying CKD was CAKUT or non-CAKUT, including apoC-II, platelet factor 4, and calmodulin, etc. A total of 20 proteins were identified: one-half was upregulated, and the other was downregulated.