NFE2L2 and melanoma: Since NRF1 and NFE2L2 have an impact on protein and mRNA levels of several ATGs and autophagy is known to play an important role in cancer, including influencing the epithelial-to-mesenchymal transition (EMT), we decided to evaluate the impact of NRF1 and NFE2L2 on the migration ability of melanoma cells (31).