The 16 genes with p < 0.05 were analyzed using a Cox proportional hazard model, which showed that high expression levels of TPD52L1 (hazard ratio [HR] = 3.218), DNAJB6 (HR = 2.37), OSBPL3 (HR = 2.128), GOLT1B (HR = 1.974), TRIM27 (HR = 1.993), PHF19 (HR = 1.965), and FNTA (HR = 1.912) were associated with a poor prognosis of CRC patients (Figure 4A). The gene discussed is TRIM27; the disease is colorectal carcinoma.