CD8A and nonpapillary renal cell carcinoma: TIMER analysis showed that mTOR expression was positively correlated with infiltrating levels of all the six TIIC subsets, i.e., macrophage (rho = 0.419, P < 0.001), neutrophil (rho = 0.432, P < 0.001), dendritic cell (rho = 0.368, P < 0.001), B cell (rho = 0.214, P < 0.001), CD8+ T cell (rho = 0.221, P < 0.001), and CD4+ T cell (rho = 0.470, P < 0.001) among the 533 ccRCC cases (Fig. 4).