Similarly, we reported the prognosis of PI3K/AKT/mTOR pathway members in ccRCC using public databases analysis, which demonstrated that mTOR mRNA were positively correlated with OS of over 500 ccRCC patients, and p-mTOR (S2448) was also positively correlated with OS in patients with ccRCC (n = 445) (Fan et al., 2020). This evidence concerns the gene MTOR and nonpapillary renal cell carcinoma.