Human superior temporal lobe AD neocortex (Brodmann A22) from CDR 1.0,(panel A, B); CDR 2.0 (panel C, D) and CDR 3.0 AD brains (panels E, F); see also[25,26]; https://knightadrc.wustl.edu/cdr/cdr.htm; (red stain;λmax=690 nm), DAPI (blue nuclear stain; λ max=470 nm) and NeuN(neuron-specific green stain; λmax=520 nm); LPS staining (red) was subjectedto co-localization analysis with the neuronal marker NeuN (green) and/or nuclearmarker (blue). The gene discussed is RBFOX3; the disease is Alzheimer disease.