MARCH3: E3 ubiquitin ligase (Fatehchand et al., 2016)/NS/available but pituitary phenotype was not investigated (Lin et al., 2018) PER2: circadian pace maker/high expression in rat pituitary gland/disrupted circardian rhythm and cancer prone (Fu et al., 2002) FLG: intermediate filament-associated protein/NS/percutaneous allergen priming (Fallon et al., 2009). The gene discussed is FLG; the disease is cancer.