COL1A1 and esophageal squamous cell carcinoma: The Kaplan–Meier survival analysis suggested good prognosis in ESCC patients with low expressions of COL1A1, SPARC, and FN1. In order to uncover the key pathway of paclitaxel resistance in ESCC, we investigated the biological function and pathways of the ESCC-specific genes in the PPI networks.