Moreover, multivariate Cox regression analysis indicated that a high NLR was an independent risk factor for renal progression after adjustment for pathologic lesions and important clinical parameters, such as the Oxford MEST-C score, sex, age, hypertension, anemia, serum albumin concentration of <30 g/L, hypertriglyceridemia, 24-hour urine protein, eGFR of <30 mL/min/1.73 m2, hyperuricemia, smoking status, hypercholesterolemia, and PLT-to-NE ratio (HR, 1.74; 95% CI, 0.98–3.05; p = 0.043) (Table 3). This evidence concerns the gene ALB and familial hypercholesterolemia.