Compared with patients without diabetes, those with diabetes had a significantly higher median (P<0.001) N-terminal pro-B type natriuretic peptide (NT-proBNP; 4,411.0 pg/mL vs 3,757.5 pg/mL), blood glucose (7.7 mmol/L vs 5.4 mmol/L), HbA1c (7.2 mmol/L vs 5.8 mmol/L), and CCI (1.0 vs 0.0), but lower eGFR (65.9 mL/min/1.73 m2 vs 76.9 mL/min/1.73 m2; P<0.001) (Table 1). The gene discussed is NPPB; the disease is diabetes mellitus.