Taken our findings and the previously apoptotic theories together, we drew the hypothesized diagram (Figure 8), which suggests that the cerebral cortex EndoG and AIF-related Caspase-independent, Fas-mediated Caspase-dependent and mitochondrial-mediated Caspase-dependent apoptotic pathways were augmented by early aged hypertension and were attenuated by EGCG treatment. Here, FAS is linked to Hypertension.