CHRM2 and heart failure: In light of these characteristics, it is plausible that the six herbal strategies possess antiviral and anti-inflammatory effect, maintain the healthy development of the heart, and prevent heart failure by targeting and regulating SLC6A2, NOS2, SLC6A4, PPARA, PPARG, CYP2C19, CYP51A1, ACHE, and CHRM2.