In conclusion, LINC01559 and SNHG8 may be coexpressed with VWF, LAMB3, LAMA4, CAV1, ALDH1A3, SMOX, GNG4, and PPARG. Additionally, these lncRNAs and mRNAs may be directly involved in the pathogenesis of childhood asthma through ECM-receptor interaction, focal adhesion, beta-alanine metabolism, PI3K-Akt signaling pathway, and pathways in cancer. This evidence concerns the gene VWF and childhood onset asthma.