BRIP1 and Fanconi anemia: BRCA1 interacting protein C-terminal helicase 1 (BRIP1) encodes a DNA helicase, also known as Fanconi Anemia group J protein (FANCJ), which plays a role within the Fanconi Anemia (FA) DNA repair pathway and has overall a broader function in maintaining genome stability by resolving DNA secondary structures [57].