CCR5 and infection: Moreover, although the inhibition in early stages has been associated with larger molecules, small alkaloid molecules with the ability to inhibit early infection processes have been also described; for example, the adhesion of the particle to the CCR5 cell receptor in the HIV model with maraviroc [39] and BMS663068 [40] or the inhibition of endosome acidification in the CHIKV model with compounds such as niclosamide and chloroquine [41].