In addition to the cyp4a10 and cyp4a14 genes that may cause NAFLD as mentioned above, we also found the high expression of cyp2e1, which can promote oxidative stress and lipid peroxidation, and lead to hepatocyte damage [30–32], accelerating the progress of NAFLD and has been reported in rats and clinical patient studies [33, 34]. The gene discussed is CYP2E1; the disease is metabolic dysfunction-associated steatotic liver disease.