High nuclear and high cytoplasmic SLC39A6 protein expression was associated with features characteristic of a good prognosis in BC, including low tumour grade (P < 0.0001 and P = 0.044, respectively), low mitotic counts (P < 0.0001, only nuclear expression), low nuclear pleomorphism (P < 0.0001 and P = 0.027), good NPI (P = 0.001 and P = 0.006) and early nodal stage (P = 0.004, only nuclear expression) (Supplementary Table 4). Here, SLC39A6 is linked to breast cancer.