Regarding the prognostic value of SLC39A6 mRNA expression, the multivariate Cox regression model including same standard prognostic factors showed its expression to be an independent predictor of BCSS in both the entire cohort (P = 0.001, HR = 0.727, 95% Cl = 0.598‒0.884) and the ER + tumours (P = 0.029, HR = 0.913, 95% Cl = 0.841‒0.991; Supplementary Table 8). This evidence concerns the gene SLC39A6 and neoplasm.