KCNMA1 and breast cancer: Having demonstrated that BK channels in the basal dendrites of BC-L5PNs are activated after Ca2+ entry through proximal NMDARs, we predicted that this coupling would give rise to a negative feedback loop similar to that described for the coupling of VGCCs and BK channels in presynaptic terminals (48) or NMDARs and small-conductance Ca2+-activated K+ channels (SK) in postsynaptic terminals (49).