AGR2 and ovarian neoplasm: The effect of eAGR2 blocking antibody on xenograft ovarian tumour growth from two other different ovarian tumour cell lines has also been investigated and showed that treatment reduced significantly the size of A2780 and SK-OV-3 xenograft ovarian tumours, which constitutively express AGR2 [47] whereas treatment had no effect on ES-2 xenograft ovarian tumours, which does not express AGR2.