So far only two articles have proposed AGR1 as a putative protein of interest in human cancer: one in gastric cancer, AGR1 would be involved in the promotion of cell growth, migration and invasion [22]; and the other in hepatocellular carcinomas, it would be involved in the promotion of Epithelial-Mesenchymal Transition (EMT) and metastasis [23]. The gene discussed is TXNDC12; the disease is hepatocellular carcinoma.