In a model of ovarian cancers, Gray et al. have described an uncoupled expression of both AGR proteins [50], it appears that AGR3 expression is associated to tumour type: in non-mucinous tumours, AGR3 expression is heterogeneous, oestrogen receptor-independent and not related to AGR2 expression, whereas in mucinous tumours, AGR2 and AGR3 stained both positive. Here, AGR3 is linked to mucinous neoplasm.