ERBB2 and neoplasm: Along with tumor size, grade, lymph node status, invasion, molecular markers including hormone receptor status and human epidermal growth factor receptor 2 (HER2) expression (Galgano et al., 2006), have an important role in screening, early diagnosis of recurrence, and treatment of many malignancies (Hellström et al., 2003; Bingle et al., 2006).