In hyperplastic polyps (group 1), there was a significant decrease in the expression of PROM1 (p: 0.01), POU5F1 (p: 0.02), LGR5 (p: 0.01) and REX1 (p: 0.01) genes compared to the control group. The gene discussed is REXO1; the disease is hyperplastic polyp.