SH2D2A and infection: The idea behind infection with ΔvRAP virus was to relieve peptide-MHC class-I complexes of the vRAP-mediated inhibition of their transport to the cell surface, and thus to enhance antigen presentation for recruiting also low-avidity virus-specific CD8+ T cells into NIF for the recognition of infected cells ([42,43] and referencing of vRAP functions therein).