Moreover, we found that although significant numbers of DC-SIGN+ B cells were present in KSHV-infected cultures, few of these DC-SIGN+ cells were KSHV infected (as shown by the expression of the GFP reporter that is constitutively expressed from the recombinant KSHV genome), indicating that infection is not particularly enriched in the DC-SIGN+ fraction (Figure 1c, right panel). This evidence concerns the gene CD209 and infection.