IL4 and COVID-19: Interestingly, while many of these cytokines and chemokines were also elevated in SARS and MERS patients, several studies have reported an increase in Th2-related anti-inflammatory cytokines IL-4 and IL-10 [115] in COVID-19 patients [113,116,117,118,119,120], ascribing a seemingly unique cytokine profile to COVID-19.