As single agents, the BH3 mimetics S63845 (MCL1i), A1331852 (BCLXL inhibitor), and ABT-263 (inhibitor of BCL2, BCLXL, and BCLW) were not universally effective in suppressing cell growth in our melanoma cell line panel (Figure 3A, Figure S1A). The gene discussed is BCL2L1; the disease is melanoma.