The effect that LMP1 exerts during NPC pathogenesis includes upregulation of the anti-apoptotic A20 and bcl-2 genes, a modulation of the morphology and motility of epithelial cells, a downregulation of metastasis suppressors, promotion of angiogenesis and activation of proinflammatory cytokines [12]. This evidence concerns the gene PDLIM7 and nasopharyngeal carcinoma.