On other hand, clear cell metastatic carcinomas (specifically clear cell renal cell carcinoma) can have the same morphology and immunohistochemistry of WCCPA [both stain for paired box gene(8) (PAX8), and to some extent to renal cell carcinoma (RCC) monoclonal antibody] [23], [24]. The gene discussed is PAX8; the disease is renal cell carcinoma.