rs10453201 is significantly associated with female osteoarthritis at any site (Psex-diff = 5.67 × 10−9, Phet-diff = 0.049; female OR = 1.05, 95% CI = 1.03–1.06, P-female = 1.05 × 10−8; male OR = 1.02, 95% CI = 1.003–1.04, P-male = 0.02) and is located 5′ of UBAP2, which has been associated with Parkinson’s disease (Nalls et al., 2019), type 2 diabetes (Xue et al., 2018), BMI (Kichaev et al., 2019), and heel bone mineral density (Morris et al., 2019) in humans. This evidence concerns the gene UBAP2 and type 2 diabetes mellitus.