IL10 and infection: Experimental research found that IL‐10 formation by CD4‐positive CD25‐positive T lymphocytes was significant for macrophage function modulation during primary infection of Brucella because the murine lacking formation of IL‐10 by T lymphocytes as well as lacking the existence of the IL‐10 receptor in macrophage cells showed diminished bacterial survival in the liver, spleen, and enhanced formation of pro‐inflammatory cytokines as well as pathology in affected organs.43