MMP2 and neoplasm: Because of the presence of PLGLAG polypeptide fragment, this hydrogel can be broken under the action of the over-expressed MMP-2 metalloproteinase in the tumor microenvironment, thus accelerating the release of CPT and the blended aPD1 antibody to induce the body to produce long-lasting anti-tumor immunity and thereby inhibit tumor recurrence and metastasis.