HSP90AB1 and interstitial lung disease: In interstitial lung disease associated with autoimmune diseases, the presence of citrullination of HSP90β is proposed to trigger an immune response mediated by specific antibodies against altered epitopes and probably by autoreactive T-cells [34,35,36,37]; also, increased levels of HSP90β is associated to worse lung function in interstitial lung disease and sclerosis [38].