miR-145 overexpression has been found to inhibit endometriotic cell proliferation, invasiveness and stemness in an in vitro endometriosis model; this was attributed to regulation of cytoskeletal elements, cell adhesion molecules, protease inhibitors and pluripotency genes (FASCIN-1, JAM-A, SOX2, SERPINE1/PAI-1, OCT4, ACTG2, TAGLN, KLF4, and PODXL) [132]. The gene discussed is SERPINE1; the disease is endometriosis.