Moreover, miR-20a targets E2F transcription factor 3 (E2F3) and Cyclin D1 (CCND1), and thus participates in epithelial cell proliferation and decreased apoptosis (antiapoptotic action); it also targets interleukin-8 (IL-8) and TGF-β, which promotes epithelial–mesenchymal transition in endometriosis. The gene discussed is E2F3; the disease is endometriosis.