NFKB1 and endometriosis: For example, miR-22-3p was found to be significantly increased in exosomes derived from peritoneal macrophages from endometriosis; it appears to be delivered from macrophages to ectopic endometrial stromal cells via exosomes, where it promotes the proliferation, migration, and invasion cells by targeting SIRT1 and activating the NF-κB pathway [84].