Treatment of CPT II deficiency consists of avoidance of known triggers (certain medications, illness, extreme cold, and extreme heat), administration of intravenous glucose and carnitines, prevention of catabolism during illness, avoidance of fasting, a high-carbohydrate and low-fat diet, and supplementation of medium chain triglycerides and vitamin D [10,20]. Here, CPT2 is linked to hyperinsulinemic hypoglycemia, familial, 4.