Previously, in an Italian study with 31 hospitalized men with COVID-19, no significant differences between SHBG levels were identified in patients who were admitted to a regular ward compared to ICU or deceased patients.[10] SHBG levels in these groups did, however, seem comparable to the levels we found.[10] The mortality rate in the Italian study was substantially lower (13%) compared to our study (44% in men) which gave our study more power to detect significant differences. Here, SHBG is linked to COVID-19.