We did not find any significant correlations between sclerostin levels and, respectively, pre-treatment GH or IGF-1 levels, current IGF-1 levels, treatment modality, use of bisphosphonates, hypogonadism or duration of remission, although for the latter, it should be noted that only two patients had a remission duration <5 years (data not shown). This evidence concerns the gene SOST and hypogonadism.