Median sclerostin concentration in controlled acromegaly patients was 104.5 pg/mL (range 45.7–234.7 pg/mL), showing comparable levels between men and women (110.0 pg/mL (range 70.0–219.2 pg/mL) in men vs 101.6 pg/ml (range 45.7–234.7 pg/mL) (p = 0.430) in women). Here, SOST is linked to acromegaly.